Pomella®’s New Research Supports Gut Health

In a new four-week trial, 250mg/day of Pomella® Pomegranate Extract was tested on healthy adults aged 25-55 (n=18, predominantly women). The study aimed to assess its impact on the gut microbiome, circulating short-chain fatty acids, and urolithins, gut-microbial derived ellagitannin metabolites, using whole genome sequencing for microbial analysis.

The results revealed that gut functional analyses are consistent with circulating short-chain fatty acids (SCFAs), reinforcing the idea that Pomella® supplementation improves SCFA levels by influencing the gut microbiome. These results imply that consuming Pomella® pomegranate extract promotes a healthier gut and improves gut-body communication.1

Expanding on these findings, researchers highlighted significant changes in short-chain fatty acids (SCFAs) pre and post Pomella® extract supplementation. They observed a 162% rise in propionate levels (p = 0.02) and a 38% increase in acetate levels (p = 0.12) following Pomella® supplementation.1

Pomella® Pomegranate Extract is a breakthrough formula developed to deliver benefits through the antioxidant polyphenols, in particular ellagitannins, such as punicalagins and their gut-derived metabolites, urolithins. With its clean-label and plant-based composition, Pomella® provides scientifically researched antioxidant benefits suitable for diverse applications, ranging from promoting gut health, cardiovascular support, cognitive and recent findings have also show strong benefits of Pomella to improving inner beauty through the gut-skin axis.

What are short chain fatty acids and why are they important? Short chain fatty acids can act as postbiotics, or the bioactive by-product of probiotics and prebiotics, in signalling from the gut to other areas of the body. In particular, butyrate, propionate, and acetate are key amino acids known to support the gut-body axes.

To learn more about Pomella® and its benefits, visit our dedicated page or contact us. Book a meeting with the team at our Vitafoods 2024 Stand (D80).


(1) Sivamani RK et al. Prospective, randomized, double-blind, placebo-controlled study of a standardized oral pomegranate extract on the gut microbiome and short-chain fatty acids. Foods. 2023 Dec 19. 13(1): 15pgs. doi: 10.3390/foods13010015