OptiMSM: Synergy with Collagen for Optimal Skin Health
- 02 July 2025
- Written by LEHVOSS Nutrition

Clinical studies demonstrate OptiMSM®'s potential on skin health, in particular OptiMSM® may reduce fine lines and wrinkles1, and improve skin texture and firmness2, with effective results seen with 1 gram dose.
It is well known that sulphur supports the skin by providing critical building blocks that the skin relies on, and also by supporting important antioxidant systems in the body to help defend against oxidative stress3.
Through their distinct mechanisms, collagen1 and sulphur4 aid in the production of collagen and other critical architectural components of the skin.
Therefore, why not bolster your collagen formula with OptiMSM®?
A recent study was set out to investigate the effects of collagen supplementation, with or without OptiMSM®, on skin health in women5 (aged 40-65), and demonstrated positive results after just 12 weeks.
This study outlined that participants who received OptiMSM® and collagen reported improvements in skin thickness, hydration and roughness5. Additionally, while supplemental collagen alone reduced skin roughness, the effect was significantly greater in the group that received both. The study concluded that combining MSM with collagen provides even greater benefits for skin health. Download the OptiMSM® and Collagen Review here.
Our OptiMSM® is a premium sulphur-rich MSM, produced in the U.S. at a dedicated facility using a proprietary multi-stage distillation process. This method removes impurities by isolating MSM molecules at specific boiling points, ensuring low moisture content and reducing the risk of contamination and degradation.
Additionally, LEHVOSS Nutrition also offer a variety of high-quality collagen options, backed by scientific research!
Discover more about OptiMSM® by visiting our dedicated page, or contact us!
References
(1) Simpson P, Benjamin R. J. Prospective Randomized, Double-Blind Study to Evaluate Dietary Supplements for Impacts on Skin Appearance in Healthy Women: Clin Exp Dermatol Res 2022; 13(5): 1000622.
(2) Anthonavage M, et al. Effects of Oral Supplementation With Methylsulfonylmethane on Skin Health and Wrinkle Reduction: Nat Med J 2015; 7(11): 1-10.
(3) Institute of Medicine, 2005. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate;
(4) National Academies of Sciences, Engineering, and Medicine. 2005. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC: The National Academies Press
(5) Pogačnik T et al. (2023) The effect of a 12-week dietary intake of food supplements containing collagen and MSM on dermis density and other skin parameters: A double-blind, placebo-controlled, randomised four-way study comparing the efficacy of three test products. doi.org/10.1016/j.jff.2023.1058.