Why Univestin® + AmLexin™ Win in Active-Aging Formulas

Univestin® and AmLexin™  work together to deliver a powerful synergy¹ for Active‑Aging formulations offering fast relief in the short term, and meaningful mobility support over time. This combined approach meets the growing demand for solutions that help consumers stay active, comfortable and confident as they age.

According to research, Univestin® provides fast‑acting support for joint comfort and mobility², helping users feel improvement within just 3-7 days, while AmLexin™ supports the long‑term preservation of cartilage integrity. Together, they may ease discomfort fast while also helping protect the structural foundation of joint health, making the combination especially relevant for active‑aging consumers who want to stay mobile and engaged throughout later life.

Research³ on Univestin® has shown significant benefits for joint stiffness and function through dual COX/LOX inhibition and strong antioxidant and anti-inflammatory support. AmLexin® has been shown to support key biomarkers associated with cartilage degradation, with one study⁴ showing that a dose of 400mg/day over 12 weeks, could significantly reduce uCTX-II (the most well-validated biomarker in osteoarthritis).

Developed through Unigen’s proprietary Phytologix® Technology Platform, Univestin® features proprietary bioflavonoids from two botanicals – Scutellaria baicalensis and heartwood of Acacia catechu – with a long history of safe human use, while AmLexin™ combines Acacia catechu heartwood extract with Morus alba root bark extract. Together, they deliver immediate comfort and long‑term joint preservation, helping brands create differentiated formulas that address the challenges of joint discomfort and cartilage wear.

To learn more about these innovative ingredients, why not download our Product Profile Sheets for Univestin® and AmLexin™, or contact us and speak to a member of the team. 

_{References
(1) Yimam M, Horm T, Wright L, Jiao P, Hong M, Brownell L, Jia Q. Cartilage Protection and Analgesic Activity of a Botanical Composition Comprised of Morus alba, Scutellaria baicalensis, and Acacia catechu. Evid Based Complement Alternat Med. 2017;2017:7059068.
(2) Arjmandi B.H., et al (2014) A Combination of Scutellaria Baicalensis and Acacia Catechu Extracts for ShortTerm Symptomatic Relief of Joint Discomfort Associated with Osteoarthritis of the Knee.
(30 Yimam M, Brownell L, Hodges M, Jia Q. Analgesic effects of a standardized bioflavonoid composition from Scutellaria baicalensis and Acacia catechu. J Diet Suppl. 2012 Sep;9(3):155-65.
(40 Kalman DS, Hewlings SJ. The Effects of Morus alba and Acacia catechu on Quality of Life and Overall Function in Adults with Osteoarthritis of the Knee. J Nutr Metab. 2017;2017:4893104. doi: 10.1155/2017/4893104. Epub 2017 Sep 11. PMID: 29085676; PMCID: PMC5612321.}