Winter Pet Comfort: Supporting Joints During Cold Months with Anivestin™

Seasonal challenges make many pet owners become more aware of their companions' mobility and joint comfort, particularly for aging. This creates an opportunity for pet nutrition brands to provide targeted support with ingredients backed by science. From Unigen®, the makers of human grade Univestin® and based on a similar joint health approach, Anivestin™ is a natural, researched plant-based composition derived from Scutellaria baicalensis and Acacia catechu. Together, these plant extracts are designed to work synergistically to help support joint comfort and mobility in companion animals¹.

What sets Anivestin™ apart is its unique combination of bioflavonoids, identified through the screening of more than 1,230 medicinal plants via Unigen’s Phytologix® library.

Research has shown these compounds help inhibit the pro-inflammatory COX and LOX pathways¹, whilst also helping to neutralise reactive oxygen species associated with inflammation and cartilage degradation^1,2. A study³ that was conducted on dogs with osteoarthritis, using a product that contained Anivestin™, demonstrated significantly greater improvements in pain scores than a chondroitin, glucosamine hydrochloride and manganese ascorbate joint-health supplement for dogs. Additionally, assessments from both veterinarians and pet owners showed Anivestin™ was more than twice as effective as the joint-health pet supplement at relieving pain at both 28 and 56 days³, highlighting its fast-acting nature and potential to support mobility throughout the colder months.

Interestingly, beyond joint health Anivestin™ has also demonstrated benefits for oral health⁴. Studies in companion animals showed significant reductions in gingivitis, gum bleeding and other measures of periodontal health⁴. This dual functionality creates opportunities for formulators looking to address multiple pet wellness needs with a single ingredient. Suitable for inclusion in treats, chews and wet foods, Anivestin™ offers a science-backed, pet-friendly solution for supporting comfort, mobility and pet’s wellbeing year-round.

Explore the science behind Anivestin™ by downloading our product profile sheet here, or contact the team to learn more.

_{References
(1) Burnett BP1, Q. Jia, Y. Zhao, R.M. Levy. 2007. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. J Med Food. 10(3):442-51.
(2) Tiku ML, Gupta S, Deshmukh DR. Aggrecan degradation in chondrocytes is mediated by reactive oxygen species and protected by antioxidants. Free Radic Res. 1999 May;30(5):395-405.
(3) Burnett BP, Stenstrom KK, Baarsch MJ, et. al. “A Flavonoid Mixture, Dual Inhibitor of Cyclooxygenase and 5-Lipoxygenase Enzymes Shows Superiority to Glucosamine/Chondroitin for Pain Management in Moderate Osteoarthritic Dogs.” International Journal of Applied Research 7.1&2 (2009): 1-12.
(4) Yimam M, Brownell L, Do SG, Lee YC, Kim DS, Seo K, Jeong M, Kim S, Jia Q. Protective Effect of UP446 on Ligature-Induced Periodontitis in Beagle Dogs. Dent J (Basel). 2019 Mar 28;7(2):33}