Revolutionary Bioavailability: Why Longvida® Is 285 Times More Effective

Longvida® Optimized Curcumin® was developed by neuroscientists at UCLA to overcome the well-known challenges of curcumin absorption. Backed by 85+ publications, its patented lipid formulation protects curcumin through digestion and enables meaningful levels to reach the bloodstream in its free, active form.

A daily 400 mg dose provides 80 mg of clinically researched curcuminoids, aligning with doses used in human studies. More than 11 clinical studies showing brain health benefits, positions Longvida® as the Cognitive Curcumin of Choice™.

Studies^1-2 show that Longvida® is 67–285 times more bioavailable than standard 95% curcumin, based on markers such as cMAX, AUC, and dose-normalized AUC.

These measures evaluate peak absorption, total systemic exposure, and dose adjusted efficiency, and they consistently demonstrate substantially higher plasma levels of free (non glucuronidated) curcumin. Research also indicates an extended half‑life of approximately 7.5 hours, compared with roughly one hour for standard curcumin¹.

Clinical studies on Longvida® have shown that just 80mg of curcuminoids may offer various health benefits. A study using 400 mg/day of Longvida® has shown improvements in attention, working memory, and mood within one hour in healthy older adults³. Additional research supports benefits in areas such as inflammation and muscle recovery⁴, joint comfort⁵, vascular function⁶, metabolic health⁷, and retinal health⁸. A study demonstrates that free curcumin can reach the retina and enable detection of retinal amyloid deposits², an important finding with relevance for Alzheimer’s‑related research. This versatility makes Longvida® suitable for a wide range of product concepts and health categories.

Longvida® is responsibly sourced through Verdure Sciences®’ Sustainable Turmeric Programme, which supports regenerative agriculture and transparent supply chains. With nearly 30 years of research, Longvida® provides a well‑researched, award‑winning curcumin solution for innovative formulations.

For more information, download our Longvida® Product Profile Sheet here or contact us.

_{References
(1) Gota et al. (2010) Safety and pharmacokinetics of a solid lipid curcumin particle formulation in patients and healthy volunteers. Journal of Agricultural and Food Chemistry: Vol 58/Issue 4
(2) Koronyo Y et al. (2017) Retinal amyloid pathology and proof-of-concept imaging trial. doi:10.1172/jci.insight.93621
(3) Cox KHM et al. (2020) Further evidence of benefits to mood and working memory from lipidated curcumin [Longvida] in healthy older people: A 12-week, double-blind, placebo-controlled, partial replication study. Nutrients. doi:10.3390/nu12061678
(4) McFarlin et al. (2016) Reduced inflammatory and muscle damage biomarkers following oral supplementation with bioavailable curcumin. doi:10.1016/j.bbacli.2016.02
(5) Gupte PA et al. (2019) Evaluation of the efficacy and safety of capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee: A pilot clinical study. doi: 10.2147/JIR.S205390
(6) Santos-Parker JR et al. (2017) Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress. doi.org/10.1093/geront/gnv554.01
(7) Lucas Fornari Laurindo et al. (2021) Curcuma longa and curcumin on metabolic syndrome: a systematic review. LCM Longhua Chinese}