New Study further supports OptiMSM® Benefits for Sports Recovery

Research has demonstrated that OptiMSM® helps with post-exercise pain and inflammation¹ and counteracts oxidative stress², supporting faster recovery after exercise.

Building on these findings, a new 2025 study³ further evaluated OptiMSM® benefits, examining 1g/day of OptiMSM® on immune response gene expression in experienced runners completing a half-marathon.

In the study, participants took either 1g of OptiMSM® or a placebo for 30 days before the race. Blood samples were collected before, and two and four hours after exercise.

Results showed improvements in exercise recovery, and antioxidant support³, highlighting OptiMSM®’s role as a methyl donor and an essential component for cellular health, aiding recovery^3,4.

Whilst a daily intake of 1g aids in recovery, earlier research demonstrates that a 3g daily dose delivers further advantages, such as greater reductions in post-exercise muscle soreness and inflammation¹. This enables athletes to tailor their post-workout support according to their individual needs.

These benefits have been observed in both new and experienced athletes, whether running on the track or lifting weights in the gym. OptiMSM® is an ideal ingredient for sports formulations at all levels, and evidence suggests it may help also counteract post-exercise immunosuppression⁵.

With more than three decades of manufacturing expertise, OptiMSM® stands out as the world’s most trusted MSM brand. Manufactured exclusively in a dedicated, single-purpose facility in North America, OptiMSM® maintains the highest standards of quality and safety. Each batch undergoes rigorous verification and independent third-party testing to ensure only the finest raw materials are used. Manufactured through a multi-stage distillation process, OptiMSM® is an exceptionally pure ingredient with a guaranteed purity of 99.9%.

In addition, OptiMSM® carries the Informed-Ingredient® Certification, providing athletes and formulators added assurance of safety for sports nutrition applications.

For more information, including additional research and available grades, visit our Health Platform or contact us.

_{(1) Kalman D, et al. A Randomized Double Blind Placebo Controlled Evaluation of MSM for Exercise Induced Discomfort/Pain: FAS EB J 2013; 27: 1076.7 (abstract).
(2) Nakhostin-Roohi B, et al. Effect of chronic supplementation with methylsulfonylmethane on oxidative stress following acute exercise in untrained healthy men: J Pharm Pharmacol 2011; 63: 1290-1294
(3) McFarlin BK et al., Using the Rise and Fall of Oxidative Stress and Inflammation Post-Exercise to Evaluate the Effect of Methylsulfonylmethane Supplementation on Immune Response mRNA. Nutrients 2025; 17: 1761
(4) Clement, K, et al., Methylsulfonylmethane Serves as a Donor of Methyl Groups for Methylation of DNA in Human Liver HepaRG Cells. J Diet Suppl 2022; 20(6), 950–962.
(5) Van der Merwe M & Bloomer RJ. The Influence of Methylsulfonylmethane on Inflammation-Associated Cytokine Release before and following Strenuous Exercise: J Sports Med 2016; 7498359}