Univestin® & AmLexin™: Synergy for Joint Health
- 31 March 2025
- Written by LEHVOSS Nutrition

Recent research highlights the synergistic benefits of AmLexin™ and Univestin® for osteoarthritis support, healthy aging and overall joint health1, by demonstrating that they can work effectively together to help reduce pain sensitivity and support the preservation of the articular cartilage matric integrity composition.
These ingredients offer an innovative, alternative natural solution for managing joint health related ailments. They are both independently backed by scientific research, which shows their efficacy for supporting joint health. Univestin® has been clinically proven to have fast-acting effects for alleviating joint discomfort and stiffness within 3-7 days, whilst AmLexin™ is known for its effectiveness in articular cartilage support. Discover more about this pioneering synergy by downloading our Univestin® & AmLexin™ Synergy Review here.
Studies specifically conducted on Univestin® demonstrated that is has beneficial effects for joint stiffness and joints functionality, caused by Osteoarthritis2. Participants were given a dose of 250 mg/day, which was proven to be significantly more effective at reducing these symptoms than the alternative anti-inflammatory drug at 200 mg/day.
Accompanying this is AmLexin™, with research to support its benefits for reducing uCTX-II (the most well-validated biomarker in osteoarthritis) by 8.9%, compared to alternative treatments3, from doses of 400 mg/day over a 12-week period.
To learn more about these innovative ingredients, visit our Health Platform or speak to a member of the team!
References
(1) Yimam M et al. (2017) Cartilage Protection and Analgesic Activity of a Botanical Composition Comprised of Morus alba, Scutellaria baicalensis, and Acacia catechu, Evid Based Complement Alternat Med. 2017 Aug 20;2017:7059068. doi: 10.1155/2017/7059068
(2) Sampalis J., L.A. Brownell. 2012. A randomized, double blind, placebo and active comparator controlled pilot study of UP446, a novel dual pathway inhibitor anti-inflammatory agent of botanical origin. Nutrition Journal. 11(21). doi:10.1186/1475-2891-11-21.
(3) Kalman DS, Hewlings SJ. The Effects of Morus alba and Acacia catechu on Quality of Life and Overall Function in Adults with Osteoarthritis of the Knee. J Nutr Metab. 2017; 2017:4893104. doi: 10.1155/2017/4893104. Epub 2017 Sep 11. PMID: 29085676; PMCID: PMC5612321.